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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Variola Virus

 
 
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High impact information on Variola Virus

  • Among the synthesized nucleosides, the adenine 2 (Neplanocin A), cytosine 14, and 5-F-cytosine 15 analogues exhibited potent anti-orthopox virus activity, including smallpox virus [1].
  • The high-energy-phosphate content, myocardial ultrastructure, left ventricular (LV) pressure, and pump function of isolated rat hearts were determined in four kinds of chronic myocardial damage induced by either autoimmunization, treatment of rats with adriamycin or noradrenaline in increasing doses, or infection with smallpox virus [2].

References

  1. Antiviral activity of cyclopentenyl nucleosides against orthopox viruses (Smallpox, monkeypox and cowpox). Chu, C.K., Jin, Y.H., Baker, R.O., Huggins, J. Bioorg. Med. Chem. Lett. (2003) [Pubmed]
  2. Cellular mechanisms of alterations in myocardial contractile function in experimental cardiomyopathies. Kapelko, V.I., Veksler, V.I., Popovich, M.I. Biomed. Sci. (1990) [Pubmed]
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