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MeSH Review:

Contig Mapping

Helou, K. et al., Manca, A. et al., Cuticchia, A.J. et al., Tang, W. et al., Hildebrandt, F. et al., et al.

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High impact information on Contig Mapping

The framework map will provide the basis for the detailed physical YAC clone contig mapping of this region, and facilitate the identification and characterization of the Sai1 locus [1].
The hDGK epsilon gene was then localized to one of the YAC clones containing a STS marker for the RP17 locus by YAC contig mapping [2].
As part of a physical and genetic study of this genomic region, we constructed a 1.5-Mb YAC contig mapping to 10q25 that contains MXI1 and ADRA2A as well as a number of STSs [3].
This contig mapping provides the basis for cloning of this interval and for isolation of the NPH1 gene [4].
In the program, PCAP, we provide a methodology for choosing synthetic oligonucleotide probes to be used in contig mapping experiments [5].

Biological context of Contig Mapping

CMAP: contig mapping and analysis package, a relational database for chromosome reconstruction [6].

References

A dual-color FISH framework map for the characterization of the Sai1 tumor suppression region on rat chromosome 5. Helou, K., Lü, X.C., Montelius-Alatalo, K., Ståhl, F., Klinga-Levan, K., Levan, G., Röhme, D. Genes Chromosomes Cancer (2000) [Pubmed]
Characterization of the human diacylglycerol kinase epsilon gene and its assessment as a candidate for inherited retinitis pigmentosa. Tang, W., Bardien, S., Bhattacharya, S.S., Prescott, S.M. Gene (1999) [Pubmed]
Detailed physical analysis of a 1.5-megabase YAC contig containing the MXI1 and ADRA2A genes. Manca, A., Volpi, E.V., Laficara, F., Muresu, R., Gray, I.C., Spurr, N.K., Nobile, C. Genomics (1997) [Pubmed]
Refined genetic mapping of a gene for familial juvenile nephronophthisis (NPH1) and physical mapping of linked markers. APN Study Group. Hildebrandt, F., Singh-Sawhney, I., Schnieders, B., Papenfuss, T., Brandis, M. Genomics (1995) [Pubmed]
PCAP: probe choice and analysis package--a set of programs to aid in choosing synthetic oligomers for contig mapping. Cuticchia, A.J., Arnold, J., Timberlake, W.E. Comput. Appl. Biosci. (1993) [Pubmed]
CMAP: contig mapping and analysis package, a relational database for chromosome reconstruction. Cuticchia, A.J., Arnold, J., Brody, H., Timberlake, W.E. Comput. Appl. Biosci. (1992) [Pubmed]

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