Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Diarrhea Virus 1, Bovine Viral

Deregt, D. et al., Tajima, M., Qi, F. et al.

Tajima,

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Disease relevance of Diarrhea Virus 1, Bovine Viral

In contrast to BVDV 1 for which conserved neutralizing epitopes have been mapped in one immunodominant domain, the virus-neutralizing E2 mAbs produced to BVDV 2 were found to bind to highly conserved epitopes in three antigenic domains [1].

High impact information on Diarrhea Virus 1, Bovine Viral

These results suggested that phylogenetic analysis of the E2 gene was more useful for identification of subgenotypes within BVDV1 [2].
Cellular ubiquitin gene is the most frequently reported insert in BVDV 1 [3].

Biological context of Diarrhea Virus 1, Bovine Viral

Except for one virus-neutralizing E2 mAb, the mAbs showed few or relatively weak cross-reactions with BVDV 1 [1].

References

Monoclonal antibodies to the E2 protein of a new genotype (type 2) of bovine viral diarrhea virus define three antigenic domains involved in neutralization. Deregt, D., van Rijn, P.A., Wiens, T.Y., van den Hurk, J. Virus Res. (1998) [Pubmed]
Bovine viral diarrhea virus 1 is classified into different subgenotypes depending on the analyzed region within the viral genome. Tajima, M. Vet. Microbiol. (2004) [Pubmed]
Insertion of a bovine SMT3B gene in NS4B and duplication of NS3 in a bovine viral diarrhea virus genome correlate with the cytopathogenicity of the virus. Qi, F., Ridpath, J.F., Berry, E.S. Virus Res. (1998) [Pubmed]

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