Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

MeSH Review:

Dog Diseases

Shibuya, H. et al., Schumacher, H.R. et al., Zhang, Q. et al., Zhang, Q. et al., Welin Henriksson, E. et al., et al.

Welin Henriksson, Hansson, Karlsson-Parra, Pettersson,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Dog Diseases

The canine disease, X-linked progressive retinal atrophy (XLPRA), is similar to human RP3, an X-linked form of retinitis pigmentosa, and maps to the same region in the X chromosome [1].
To date no initiating agent has been identified, but this spontaneous canine disease which is very similar to human RA can provide a valuable model in which to examine pathogenesis of chronic arthritis [2].
The comparable region of the human X chromosome includes the disease locus for RP3, an X-linked form of retinitis pigmentosa, although the current canine disease interval is much larger [3].
Moreover, alleles of the canine CLN3 gene distinguished by an intragenic marker segregated independently from the disease in an English setter family, eliminating CLN3 as the locus for the canine disease [4].
No significant cross reactivity was observed with sera of animals with other common canine diseases [5].

Gene context of Dog Diseases

Canine systemic lupus erythematosus (SLE) has a similar disease expression as human SLE, but the serological characterisation of the canine disease is as yet incomplete [6].

References

Different RPGR exon ORF15 mutations in Canids provide insights into photoreceptor cell degeneration. Zhang, Q., Acland, G.M., Wu, W.X., Johnson, J.L., Pearce-Kelling, S., Tulloch, B., Vervoort, R., Wright, A.F., Aguirre, G.D. Hum. Mol. Genet. (2002) [Pubmed]
Synovial pathologic changes in spontaneous canine rheumatoid-like arthritis. Schumacher, H.R., Newton, C., Halliwell, R.E. Arthritis Rheum. (1980) [Pubmed]
Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals. Zhang, Q., Acland, G.M., Zangerl, B., Johnson, J.L., Mao, Z., Zeiss, C.J., Ostrander, E.A., Aguirre, G.D. Invest. Ophthalmol. Vis. Sci. (2001) [Pubmed]
Coding sequence and exon/intron organization of the canine CLN3 (Batten disease) gene and its exclusion as the locus for ceroid-lipofuscinosis in English setter dogs. Shibuya, H., Liu, P.C., Katz, M.L., Siakotos, A.N., Nonneman, D.J., Johnson, G.S. J. Neurosci. Res. (1998) [Pubmed]
Diagnosis of American visceral leishmaniasis in humans and dogs using the recombinant Leishmania donovani A2 antigen. Carvalho, F.A., Charest, H., Tavares, C.A., Matlashewski, G., Valente, E.P., Rabello, A., Gazzinelli, R.T., Fernandes, A.P. Diagn. Microbiol. Infect. Dis. (2002) [Pubmed]
Autoantibody profiles in canine ANA-positive sera investigated by immunoblot and ELISA. Welin Henriksson, E., Hansson, H., Karlsson-Parra, A., Pettersson, I. Vet. Immunol. Immunopathol. (1998) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share