Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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MeSH Review:

Mediastinal Neoplasms

Levine, G.D. et al., Gao, Z. et al., Butler, M.H. et al., Magnan, P.E. et al., Hoffman, O.A. et al.

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Disease relevance of Mediastinal Neoplasms

Obstruction of the superior vena cava was caused by pulmonary or mediastinal cancer in nine patients and chronic mediastinitis in one [1].

High impact information on Mediastinal Neoplasms

We report here the identification of high-titer autoantibodies directed against gephyrin in a patient with clinical features of SMS and mediastinal cancer [2].
Primary mediastinal neoplasms (other than thymoma) [3].
This variant seems to behave in an aggressive fashion and should be under the differential diagnoses of mediastinal neoplasm with prominent mucin production [4].

Analytical, diagnostic and therapeutic context of Mediastinal Neoplasms

Radiotherapy, even for apparently encapsulated cases, may be indicated for this aggressive mediastinal neoplasm, which can be clearly separated from the thymoma by clinical, histologic, and fine structural criteria [5].

References

Surgical reconstruction of the superior vena cava. Magnan, P.E., Thomas, P., Giudicelli, R., Fuentes, P., Branchereau, A. Cardiovascular surgery (London, England) (1994) [Pubmed]
Autoimmunity to gephyrin in Stiff-Man syndrome. Butler, M.H., Hayashi, A., Ohkoshi, N., Villmann, C., Becker, C.M., Feng, G., De Camilli, P., Solimena, M. Neuron (2000) [Pubmed]
Primary mediastinal neoplasms (other than thymoma). Hoffman, O.A., Gillespie, D.J., Aughenbaugh, G.L., Brown, L.R. Mayo Clin. Proc. (1993) [Pubmed]
Thymic carcinoid with mucinous stroma: a rare variant of carcinoid with an aggressive clinical course. Gao, Z., Kahn, L., Bhuiya, T. Annals of diagnostic pathology. (2006) [Pubmed]
A spindle cell varient of thymic carcinoid tumor. A clinical, histologic, and fine structural study with emphasis on its distinction from spindle cell thymoma. Levine, G.D., Rosai, J. Arch. Pathol. Lab. Med. (1976) [Pubmed]

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