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MeSH Review:

Abortion, Eugenic

Giordano, P.C. et al., Barron, S.L., Furu, T. et al., Wertz, D.C. et al., Wedekind, C. et al., et al.

Giordano, Dihal, Harteveld,

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Disease relevance of Abortion, Eugenic

Attitudes towards prenatal diagnosis and selective abortion among patients with retinitis pigmentosa or choroideremia as well as among their relatives [1].
A survey in the Northern Region of England, with official statistics from Scotland, shows that in spite of the contribution made by selective abortion, there appears to be a genuine reduction in the population incidence of neural tube defect in Scotland [2].

High impact information on Abortion, Eugenic

The majority of affected families reject selective abortion for CF; many will curtail childbearing rather than use prenatal diagnosis [3].
The MHC has been found to influence mate choice and selective abortions in mice and humans [4].
Selective abortion for familial Alzheimer disease [5]?
We also interviewed 105 informed individuals of different ethnicities, all members of the multi-ethnic patients and carriers' organization 'OSCAR Nederland'. RESULTS: On average, 68% of the Surinamese Hindustanis and 42% of the Surinamese Afro-Americans were in favor of selective abortion in case of affected pregnancy [6].

References

Attitudes towards prenatal diagnosis and selective abortion among patients with retinitis pigmentosa or choroideremia as well as among their relatives. Furu, T., Kääriäinen, H., Sankila, E.M., Norio, R. Clin. Genet. (1993) [Pubmed]
Some aspects of late abortion for congenital abnormality. Barron, S.L. Ciba Found. Symp. (1985) [Pubmed]
Attitudes toward the prenatal diagnosis of cystic fibrosis: factors in decision making among affected families. Wertz, D.C., Janes, S.R., Rosenfield, J.M., Erbe, R.W. Am. J. Hum. Genet. (1992) [Pubmed]
Non-random fertilization in mice correlates with the MHC and something else. Wedekind, C., Chapuisat, M., Macas, E., Rülicke, T. Heredity (1996) [Pubmed]
Selective abortion for familial Alzheimer disease? Post, S.G., Botkin, J.R., Whitehouse, P. Obstetrics and gynecology. (1992) [Pubmed]
Estimating the attitude of immigrants toward primary prevention of the hemoglobinopathies. Giordano, P.C., Dihal, A.A., Harteveld, C.L. Prenat. Diagn. (2005) [Pubmed]

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