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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Myofascial TMD does not run in families.

This study tests whether facial pain or associated symptoms and disorders aggregates in first degree relatives of those with myofascial temporomandibular disorders (M/ TMD). We randomly selected one first degree relative of 106 probands with a lifetime history of M/ TMD and one first degree relative of 118 acquaintance control probands with no history of M/ TMD. Relatives were directly interviewed about the lifetime occurrence of a broad range of painful and non-painful health conditions and symptoms. Analyses revealed that rates of facial pain, symptoms of TMDs, and a range of other musculoskeletal conditions were not significantly different in first degree relatives of M/ TMD probands and first degree relatives of controls. In addition, proband descriptors of facial pain severity or disability did not significantly predict the likelihood of having a first degree relative with one or more TMD-related symptoms. These results indicate that M/ TMD is not a familial disorder.[1]

References

  1. Myofascial TMD does not run in families. Raphael, K.G., Marbach, J.J., Gallagher, R.M., Dohrenwend, B.P. Pain (1999) [Pubmed]
 
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