Disease relevance of Temporomandibular Joint Disorders

• This study tests whether facial pain or associated symptoms and disorders aggregates in first degree relatives of those with myofascial temporomandibular disorders (M/TMD) [1].
• Discernible dental attrition in a non-patient population was not associated with signs and symptoms of temporomandibular disorders, nor with the occlusal factors studied [2].
• Patients with open bite often show a weak occlusal force and temporomandibular disorders (TMDs) [3].
• An analysis of exclusively representative population-based studies on adults has shown that only few and inconsistent associations could be detected between malocclusions and clinical signs of temporomandibular disorders (TMD)--and none for functional occlusion factors (occlusal interferences, non-working side contacts, etc) [4].
• Occlusal variables, bruxism and temporomandibular disorders: a clinical and kinesiographic assessment [5].

Psychiatry related information on Temporomandibular Joint Disorders

• AIMS: To evaluate short-term patient compliance with 5 conservative temporomandibular disorder (TMD) treatments (jaw relaxation, jaw stretching, heat application, cold application, and occlusal splint use) and the association of compliance with changes in pain intensity, pain-related activity interference, and jaw use limitations [6].
• AIMS: To develop a German-language version of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) through a formal translation/back-translation process, to summarize available data about their psychometric properties, and to provide new data about psychometric testing of components of the RDC/TMD [7].
• All patients received 2 standarized questionnaires, the Eating Attitudes Test 26 (EAT-26) and the Hapak questionnaire, to determine the presence of symptoms associated with an eating disorder or a temporomandibular disorder, respectively [8].

High impact information on Temporomandibular Joint Disorders

• Such a SP release may play an important role in determining the trigeminal inflammatory allodynia concerning the temporomandibular disorder [9].
• Celecoxib showed slightly better pain reduction than placebo, but was not significantly effective for temporomandibular disorder pain [10].
• Occlusal treatments in temporomandibular disorders: a qualitative systematic review of randomized controlled trials [11].
• Basal circadian cortisol secretion in women with temporomandibular disorders [12].
• Possible involvement of histamine in muscular fatigue in temporomandibular disorders: animal and human studies [13].

Chemical compound and disease context of Temporomandibular Joint Disorders

• We also examined the effect of an antihistamine, chlorphenylamine (CP), on temporomandibular disorders in humans and compared it with that of an anti-inflammatory analgesic, flurbiprofen (FB) [13].
• This double-blind study evaluated the short-term effect of iontophoretic delivery of dexamethasone on the signs and symptoms of temporomandibular disorders in patients who had concurrent temporomandibular joint disc displacement without reduction and capsulitis [14].
• The expression of an estrogen receptor alpha-immunoreaction in the fibroblast-like type B cells may explain the etiology of temporomandibular disorders at a higher frequency in females than in males, suggesting that TMJ is a target tissue for estrogen [15].
• OBJECTIVE: The purpose of this study was to assess the potential for improved lesion detection in the posterior disk attachment and its surrounding tissue in temporomandibular disorders when gadolinium-enhanced MR imaging performed with fat suppression is used [16].
• Thus, iron-dependent generation of HO( *) might have a crucial role in the pathogenesis of temporomandibular disorders [17].

Biological context of Temporomandibular Joint Disorders

• Application of principles of evidence-based medicine to occlusal treatment for temporomandibular disorders: are there lessons to be learned [18]?
• A case series of temporomandibular disorders treated with acupuncture, occlusal splint and point injection therapy [19].
• Although these symptoms could be aspects of Eagle's syndrome, deflective occlusal interferences, tender muscles of mastication, and a clicking temporomandibular joint led to an evaluation for temporomandibular disorder related to malocclusion [20].
• Scientific methodology in temporomandibular disorders. Part I: Epidemiology [21].

Anatomical context of Temporomandibular Joint Disorders

• The differential induction of Fos expression suggests that an increase in TMJ C-fiber input after inflammation and robust central neuronal hyperexcitability contribute to persistent pain associated with temporomandibular disorders [22].
• As an approach to clarifying the molecular basis of pain and fatigue in muscles involved in temporomandibular disorders, we examined the activity of histidine decarboxylase (HDC), the enzyme which forms histamine, in the masseter muscles of mice [13].
• Among them, the 5,5-dimethyl-1-pyrroline-N-oxide (DMPO)-OH spectrum was the most prominent, suggesting that HO(*) was dominantly generated in the synovial fluid from temporomandibular disorder patients [17].
• MATERIAL AND METHODS: The mandibular movements of 35 subjects diagnosed with temporomandibular disorders were recorded with 2 CCD cameras, and sounds were recorded bilaterally with Panasonic electret condenser microphones in the ear canal [23].

Gene context of Temporomandibular Joint Disorders

• IL-1 beta, IL-1 receptor antagonist and soluble type II IL-1 receptor in synovial fluid of patients with temporomandibular disorders [24].
• Determination of interleukin-1 receptor antagonist, interleukin-10, and transforming growth factor-beta1 in synovial fluid aspirates of patients with temporomandibular disorders [25].
• These studies suggest that ghrelin, a multifunctional peptide, may contribute to the mechanism linking orofacial pain syndromes in females, including temporomandibular disorder and migraine, to cyclical hormonal changes [26].
• A 3-year follow-up of temporomandibular disorders in rheumatoid arthritis and ankylosing spondylitis [27].
• On the basis of these and previous results and the known actions of histamine, we propose that the histamine newly formed following the induction of HDC activity, which is itself mediated by IL-1, may be involved in inducing pain and, possibly, stiffness in muscles in temporomandibular disorders [13].

Analytical, diagnostic and therapeutic context of Temporomandibular Joint Disorders

• The purpose of this study was to evaluate the effectiveness of the therapy with occlusal splints in patients with temporomandibular disorders by the computerized electromyography [28].
• Treatment outcome of headache after occlusal appliance therapy in a randomised controlled trial among patients with temporomandibular disorders of mainly arthrogenous origin [29].
• Emergency treatment of acute temporomandibular disorders: Part 1 [30].
• This study suggests that occlusal splint therapy is a more effective treatment for the pain, tenderness, and limited mandibular opening associated with temporomandibular disorders than relaxation therapy [31].
• The purpose of this article is to review the literature on the relationship between occlusal discrepancies and temporomandibular disorders (TMD) and to summarize the guidelines of treating TMD by prosthetic rehabilitation [32].

References