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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Triterpene trimers from Maytenus scutioides: cycloaddition compounds?

Two novel trimers, triscutins A and B (1 and 2), based on pristimerin triterpene units, were isolated and characterized from Maytenus scutioides. Their structures were determined on the basis of spectroscopic evidence, including 1H-13C heteronuclear correlation (HMQC), long-range correlation with inverse detection (HMBC), and ROESY NMR experiments; and their absolute configurations, by means of CD studies. Compounds 1 and 2 were assayed for antimicrobial and cytotoxic activities, and their possible biosynthetic route is proposed.[1]


  1. Triterpene trimers from Maytenus scutioides: cycloaddition compounds? González, A.G., Alvarenga, N.L., Bazzocchi, I.L., Ravelo, A.G., Moujir, L. J. Nat. Prod. (1999) [Pubmed]
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