The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Pristimerin     methyl (2R,4aS,6aS,6aR,14aS,14bR)- 10...

Synonyms: GNF-PF-476, CHEMBL54804, SureCN15020, BSPBio_003401, KBioGR_001942, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of C08633

 

High impact information on C08633

 

Anatomical context of C08633

 

Associations of C08633 with other chemical compounds

  • A new quinonemethide triterpene named as salacin, has been isolated from the root bark of Salacia campestris in addition to the known pristimerin, maytenin, 20alpha-hydroxymaytenin, and netzahualcoyene [6].
 

Analytical, diagnostic and therapeutic context of C08633

References

  1. Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria. Wu, C.C., Chan, M.L., Chen, W.Y., Tsai, C.Y., Chang, F.R., Wu, Y.C. Mol. Cancer Ther. (2005) [Pubmed]
  2. Structural basis of potent antiperoxidation activity of the triterpene celastrol in mitochondria: effect of negative membrane surface charge on lipid peroxidation. Sassa, H., Kogure, K., Takaishi, Y., Terada, H. Free Radic. Biol. Med. (1994) [Pubmed]
  3. The triterpenoid quinonemethide pristimerin inhibits induction of inducible nitric oxide synthase in murine macrophages. Dirsch, V.M., Kiemer, A.K., Wagner, H., Vollmar, A.M. Eur. J. Pharmacol. (1997) [Pubmed]
  4. Insecticidal activity of Maytenus species (Celastraceae) nortriterpene quinone methides against codling moth, Cydia pomonella (L.) (Lepidoptera: tortricidae). Avilla, J., Teixidò, A., Velázquez, C., Alvarenga, N., Ferro, E., Canela, R. J. Agric. Food Chem. (2000) [Pubmed]
  5. Novel quinone methides from Salacia kraussii with in vitro antimalarial activity. Figueiredo, J.N., Räz, B., Séquin, U. J. Nat. Prod. (1998) [Pubmed]
  6. Antioxidant quinonemethide triterpenes from Salacia campestris. Carvalho, P.R., Silva, D.H., Bolzani, V.S., Furlan, M. Chem. Biodivers. (2005) [Pubmed]
 
WikiGenes - Universities