Disease relevance of Maytenus

• A new macrolide antibiotic with antitumor activity produced by Streptomyces sp. CS, a commensal microbe of Maytenus hookeri [1].
• The two triterpenes isolated from the leaves of Maytenus ilicifolia, did not decrease gastric ulcers when tested on indometacine induced ulcer model in rats [2].

High impact information on Maytenus

• A lyophilized aqueous extract of Maytenus ilicifolia leaves inhibits histamine-mediated acid secretion in isolated frog gastric mucosa [3].
• Maytoline, maytine, and maytolidine, novel nicotinoyl sesquiterpene alkaloids from Maytenus serrata (Hochst., ex A. Rich.) R. Wilczek [4].
• We have found that dihydro-beta-agarofuran sesquiterpenes from Maytenus cuzcoina inhibited Hoechst 33342 transport that correlates with their reversal effect in a multidrug-resistant L. tropica line overexpressing Pgp [5].
• Gymnosporia and Tricerma are distinct from Maytenus, Cassine is supported as distinct from Elaeodendron, and Dicarpellum is distinct from Salacia [6].
• Spermidine alkaloids and triterpenes from Maytenus heterophylla and Pleurostylia africana. Chemical constituents of the Celastraceae--IV [7].

Biological context of Maytenus

• The aim of this study is to evaluate the efficacy (anti-inflammatory and antinociceptive activities and protection against gastric lesions, including cytoprotection and healing) and phytochemical profile of hexane and ethylacetate extracts of Maytenus ilicifolia [8].

Anatomical context of Maytenus

• A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa [9].
• Extracts of different polarity from Baccharis trimera, Haplopappus rigidus Huperzia saururus, Maytenus ilicifolia, Satureja parvifolia and Senecio eriophyton were tested for their relaxant activity on smooth muscle using L-phenylephrine precontracted strips of corpus cavernosum obtained from Guinea pigs [10].

Associations of Maytenus with chemical compounds

• Insecticidal sesquiterpene pyridine alkaloids from Maytenus chiapensis [11].
• Friedelane triterpenoids from Maytenus macrocarpa [9].
• Previously, we isolated two new flavonoid tetrasaccharides from the infusion of Maytenus aquifolium leaves that showed antiulcer activity [12].
• Two novel trimers, triscutins A and B (1 and 2), based on pristimerin triterpene units, were isolated and characterized from Maytenus scutioides [13].
• A new antibiotic nortriterpene quinone methide from Maytenus catingarum [14].

Gene context of Maytenus

• Effect of Maytenus ilicifolia Mart. on pregnant mice [15].
• DNA polymerase beta lyase inhibitors from Maytenus putterlickoides [16].
• Antioxidant activity of Maytenus ilicifolia root bark [17].
• A method for the quantification of aflatoxins B1, G1, B2 and G2 in the medicinal herb Maytenus ilicifolia was developed and validated [18].

Analytical, diagnostic and therapeutic context of Maytenus

• The antimutagenic activity of two plants Maytenus ilicifolia and Peltastes peltatus, both rich in compounds of the flavonoid and tannin groups and frequently employed in folk medicine, was studied [19].

References