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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Intoxication due to negative canrenone interference in digoxin drug monitoring.

Canrenone and spironolactone caused falsely low readings in a common assay for digoxin (AxSym MEIA) due to negative cross-reactivity. Misleading subtarget concentrations were repeatedly reported, and falsely guided drug dosing resulted in a case of digoxin intoxication.[1]

References

  1. Intoxication due to negative canrenone interference in digoxin drug monitoring. Steimer, W., Müller, C., Eber, B., Emmanuilidis, K. Lancet (1999) [Pubmed]
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