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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Delayed akathisia and suicidal attempts following epidural droperidol infusion--a case report.

Epidural administration of droperidol has been used to prevent postoperative nausea and vomiting (PONV) caused by opioids, but the adverse reactions were relatively neglected. We present a patient who received patient-controlled epidural analgesia (PCEA) with bupivacaine-morphine-droperidol mixture for one and half days following hemorrhoidectomy, developed paroxysmal adverse reactions of akathisia, dysphoria, and suicidal attempts 3 days after the initiation of the treatment. The use of droperidol in PCEA for prevention of nausea and vomiting therefore needs to be re-evaluated according to the serious side effects occurring in our case.[1]

References

  1. Delayed akathisia and suicidal attempts following epidural droperidol infusion--a case report. Hung, Y.C., Ho, Y.Y., Shen, C.L. Acta Anaesthesiol. Sin. (1999) [Pubmed]
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