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Setzer, W.N. et al.

Setzer, Shen, Bates, Burns, McClure, Zhang, Moriarity, Lawton,

A phytochemical investigation of Alchornea latifolia.

A phytochemical investigation of the chloroform leaf extract of Alchornea latifolia has been undertaken. Along with the triterpenoids taraxerone, friedelin, epifriedelinol, and taraxerol, the plant also contains seco-3,4-friedelin (dihydroputranjivic acid) (1) and seco-3,4-taraxerone (2). These A-ring-opened triterpenoids show in vitro cytotoxic activity against Hep-G2 and A-431 human cancer cell lines and are potent inhibitors of topoisomerase II.[1]

References

A phytochemical investigation of Alchornea latifolia. Setzer, W.N., Shen, X., Bates, R.B., Burns, J.R., McClure, K.J., Zhang, P., Moriarity, D.M., Lawton, R.O. Fitoterapia (2000) [Pubmed]

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