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Bassetti, M. et al.

Bassetti, Manno, Collidà, Ferrando, Gatti, Ugolotti, Cruciani, Bassetti,

Erythromycin resistance in Streptococcus pyogenes in Italy.

In a prospective study of acute pharyngitis in Italian children, 69 (38.3%) of 180 isolates of Streptococcus pyogenes were resistant to macrolides. S. pyogenes was eradicated in 12 (63.1%) of 19 patients with erythromycin-resistant S. pyogenes treated with clarithromycin and in 22 (88%) of 25 patients with erythromycin-susceptible strains. The constitutive-resistant phenotype was correlated with failure of macrolide treatment.[1]

References

Erythromycin resistance in Streptococcus pyogenes in Italy. Bassetti, M., Manno, G., Collidà, A., Ferrando, A., Gatti, G., Ugolotti, E., Cruciani, M., Bassetti, D. Emerging Infect. Dis. (2000) [Pubmed]

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