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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Impact of the development of agricultural land on the transmission of sleeping sickness in Daloa, Côte d'Ivoire.

Although tools to control sleeping sickness do exist, their use is difficult; areas where intervention is most required often cannot be targeted for lack of appropriate risk indicators. The importance of human behaviour and habits in the manifestation of the disease is clear. In the development of effective new approaches to the control of the disease, information must be gathered about human populations, and their interaction with the environment, in rural as well as in urban and peri-urban areas. The results of a study carried out in Daloa show that use of some methods for the development of agricultural land leads to increased human-vector contact and, as a result, increased risk of sleeping sickness. Such land-management methods may therefore be useful as risk indicators for transmission. Transmission does not occur in the town of Daloa itself but in surrounding areas under cultivation. The use of the epidemiological risk index seems to be inappropriate in urban (and perhaps peri-urban) areas. The results emphasise not only the importance of environmental and demographic data in elucidating the epidemiology of human trypanosomiasis but also the need for further investigations in peri-urban areas.[1]


  1. Impact of the development of agricultural land on the transmission of sleeping sickness in Daloa, Côte d'Ivoire. Fournet, F., Traore, S., Prost, A., Cadot, E., Hervouët, J.P. Ann. Trop. Med. Parasitol. (2000) [Pubmed]
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