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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Structure and antiprotozoal activity of triterpenoid saponins from Glinus oppositifolius.

Two new triterpenoid saponins, glinosides A and B, isolated from the aerial parts of Glinus oppositifolius, have been characterized by 1D, 2D, NMR and high-resolution mass spectral (HRMS) techniques. Their structures were established respectively as 16-O-(beta-arabinopyranosyl)-3-oxo-12,16 beta,21 beta,22-tetrahydroxyhopane for glinoside A and 16-O-(beta-arabinopyranosyl)-3-oxo-12,16 beta,22-trihydroxyhopane for glinoside B. Results presented evidence that fractions had a better antiplasmodial activity (IC50 = 31.80 micrograms/ml) than pure glinoside A (IC50 = 42.30 micrograms/ml).[1]

References

  1. Structure and antiprotozoal activity of triterpenoid saponins from Glinus oppositifolius. Traore, F., Faure, R., Ollivier, E., Gasquet, M., Azas, N., Debrauwer, L., Keita, A., Timon-David, P., Balansard, G. Planta Med. (2000) [Pubmed]
 
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