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MeSH Review:

Molluginaceae

Endale, A. et al., Kolkmann, R. et al., Kavimani, S. et al., Rajasekaran, M. et al., Traore, F. et al., et al.

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Disease relevance of Molluginaceae

Enzyme preparations from Mycobacterium phlei, Escherichia coli and Galium mollugo cell suspension cultures were incubated in the presence of 4-(2'-carboxyphenyl)-4-oxobutyrate (i.e. o-succinylbenzoic acid, OSB, 1), ATP, coenzyme A and Mg2+ [1].
The antitumour activity of the methanolic extract of Glinus lotoides (MGL) has been evaluated against Dalton's ascitic lymphoma (DAL) in Swiss albino mice [2].

High impact information on Molluginaceae

Structure and antiprotozoal activity of triterpenoid saponins from Glinus oppositifolius [3].
Seven hopane-type saponins were isolated from the methanol extract of Glinus lotoides [4].
Four new hopane-type saponins, glinusides F, G, H, and I (1-4), and the known succulentoside B (5), as well as the two known flavones 5,7,4'-trihydroxyflavone-6,8-di-C-glucoside (vicenin-2) and 5,7,4'-trihydroxyflavone-8-C-sophoroside (vitexin-2' '-O-glucoside), were isolated from the seeds of Glinus lotoides growing in Ethiopia [5].
The ethyl acetate fraction of Mollugo pentaphylla, a tropical herb, contains an antifungal saponin (mollugogenol-A) [6].

References

4-(2'-Carboxyphenyl)-4-oxobutyryl coenzyme A ester, an intermediate in vitamin K2 (menaquinone) biosynthesis. Kolkmann, R., Leistner, E. Z. Naturforsch., C, J. Biosci. (1987) [Pubmed]
Effect of the methanolic extract of Glinus lotoides on Dalton's ascitic lymphoma. Kavimani, S., Manisenthilkumar, K.T., Ilango, R., Krishnamoorthy, G. Biol. Pharm. Bull. (1999) [Pubmed]
Structure and antiprotozoal activity of triterpenoid saponins from Glinus oppositifolius. Traore, F., Faure, R., Ollivier, E., Gasquet, M., Azas, N., Debrauwer, L., Keita, A., Timon-David, P., Balansard, G. Planta Med. (2000) [Pubmed]
Hopane-type saponins from Glinus lotoides Linn. Biswas, T., Gupta, M., Achari, B., Pal, B.C. Phytochemistry (2005) [Pubmed]
Hopane-type saponins from the seeds of Glinus lotoides. Endale, A., Wray, V., Murillo, R., Schmidt, P.C., Merfort, I. J. Nat. Prod. (2005) [Pubmed]
Spermicidal activity of an antifungal saponin obtained from the tropical herb Mollugo pentaphylla. Rajasekaran, M., Nair, A.G., Hellstrom, W.J., Sikka, S.C. Contraception. (1993) [Pubmed]

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