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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Total syntheses of (-)-fumiquinazolines A, B, and I.

[structure] The first total syntheses of (-)-fumiquinazolines A, B, and I have been accomplished efficiently using the Pd-catalyzed cyclization of an iodoindole carbamate to construct the imidazoindolone moiety and the dehydrative cyclization of a diamide followed by rearrangement through an amidine to construct the quinazolone moiety.[1]


  1. Total syntheses of (-)-fumiquinazolines A, B, and I. Snider, B.B., Zeng, H. Org. Lett. (2000) [Pubmed]
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