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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Ep-CAM overexpression in breast cancer as a predictor of survival.

The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.[1]


  1. Ep-CAM overexpression in breast cancer as a predictor of survival. Gastl, G., Spizzo, G., Obrist, P., Dünser, M., Mikuz, G. Lancet (2000) [Pubmed]
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