Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Mrochen, M. et al.

Mrochen, Kaemmerer, Mierdel, Seiler,

Increased higher-order optical aberrations after laser refractive surgery: a problem of subclinical decentration.

PURPOSE: To study the clinical and theoretical effects of subclinical decentrations on the optical performance of the eye after photorefractive laser surgery. SETTING: Department of Ophthalmology, University of Dresden, Dresden, Germany. METHODS: Ocular aberrations were determined before and 1 month after uneventful photorefractive keratectomy (PRK) with the Multiscan laser (Schwind) in 10 eyes of 8 patients. The corrections ranged from -2.5 to -6.0 diopters, and ablation zones of 6.0 mm and larger were used. The measured wavefront errors were compared to numerical simulations using the individually determined decentrations and currently used ablation profiles. RESULTS: The PRK-induced aberrations were significantly greater than the preoperative aberrations. The numerically calculated increase in the higher-order optical aberrations correlated with the clinical results, demonstrating a major increase in coma- and spherical-like aberrations. Subclinical decentration (less than 1.0 mm) was found to be a major factor in increased coma-like and spherical-like aberrations after corneal laser surgery. CONCLUSION: To minimize higher-order optical errors, special efforts to center the ablation zone are necessary; for example, by eye-tracking systems that consider the visual axis.[1]

References

Increased higher-order optical aberrations after laser refractive surgery: a problem of subclinical decentration. Mrochen, M., Kaemmerer, M., Mierdel, P., Seiler, T. Journal of cataract and refractive surgery. (2001) [Pubmed]

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