Feeding tolerance of ready-to-use versus powdered formulas in neonates.
BACKGROUND: Following the introduction of ready-to-use formula in our neonatal department, we observed an increase in the number of neonates regurgitating after feeding. OBJECTIVE: To compare the feeding tolerance of neonates, in terms of regurgitations, to ready-to-use versus powdered formulas. METHODS: We compared the number of regurgitations in 727 healthy neonates after feeding ready-to-use formulas and powdered formulas of two different manufacturers. Six groups of neonates were formed, three for each manufacturer. Each of the two groups was fed with either ready-to-use formula or with reconstructed powdered formula (using a two-compartment patented feeding bottle called Twist 'N Feed) and one group received both preparations during 2 successive days. RESULTS: The groups that were fed only with ready-to-use formulas had significantly more regurgitations than those fed with powdered formulas. Within the group that received both types of formulas there were significantly more regurgitations following the ready-to-use than the powdered formula. CONCLUSIONS: Feeding tolerance, in terms of regurgitations, was significantly better in neonates fed reconstituted powdered formula as opposed to ready-to-use formulas. More studies are required to determine the exact mechanism for these differences.[1]References
- Feeding tolerance of ready-to-use versus powdered formulas in neonates. Weisbrod, M., Mimouni, F.B. Isr. Med. Assoc. J. (2000) [Pubmed]
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