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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists.

A series of 1,4-benzodiazepines, N-1-substituted with an N-isopropyl-N-phenylacetamide moiety, was synthesized and screened for CCK-A agonist activity. In vitro agonist activity on isolated guinea pig gallbladder along with in vivo induction of satiety following intraperitoneal administration in a rat feeding assay was demonstrated.[1]

References

  1. 1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists. Sherrill, R.G., Berman, J.M., Birkemo, L., Croom, D.K., Dezube, M., Ervin, G.N., Grizzle, M.K., James, M.K., Johnson, M.F., Queen, K.L., Rimele, T.J., Vanmiddlesworth, F., Sugg, E.E. Bioorg. Med. Chem. Lett. (2001) [Pubmed]
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