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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies.

We investigated serological immune responses against three major peripheral nerve myelin constituents in patients with immune-mediated neuropathies. Connexin 32 (Cx32), myelin protein zero (MPZ, P(0)) and peripheral myelin protein 22 (PMP22) were produced in Chinese hamster ovary (CHO)-K1 cells. From a panel of 25 Guillain-Barré syndrome (GBS) and 24 chronic inflammatory demyelinating polyneuropathy (CIDP) patients, only two patients showed reactivity towards Cx32 and P(0).[1]

References

  1. Investigation of serum response to PMP22, connexin 32 and P(0) in inflammatory neuropathies. Kwa, M.S., van Schaik, I.N., Brand, A., Baas, F., Vermeulen, M. J. Neuroimmunol. (2001) [Pubmed]
 
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