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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Frisch, S.M. et al.

Frisch, Screaton,

Anoikis mechanisms.

Anoikis is defined as apoptosis that is induced by inadequate or inappropriate cell-matrix interactions. It is involved in a wide diversity of tissue-homeostatic, developmental and oncogenic processes. The central problem of anoikis is to understand how integrin-mediated cell adhesion signals control the apoptotic machinery. In particular, the initiation of the caspase cascade in anoikis remains to be explained.[1]

References

Anoikis mechanisms. Frisch, S.M., Screaton, R.A. Curr. Opin. Cell Biol. (2001) [Pubmed]

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