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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Amperometric determination of dipyrone in pharmaceutical formulations with a flow cell containing gold electrodes from recordable compact discs.

A simple, rapid, and precise amperometric method for quantification of dipyrone in pharmaceutical formulations is presented. The proposed method permits determinations in the 10(-7) mol L(-1) of the analyte and enables 90 determinations h(-1), employing only 100 microL of sample per determination. This method is based on the direct quantification of dipyrone in many pharmaceutical products, avoiding cumbersome processes such as previous separations, solvent extraction, or sample filtration. This new procedure was applied to commercial pharmaceutical tablets, and the results obtained were in excellent agreement with the ones obtained by the classical iodometric method.[1]

References

  1. Amperometric determination of dipyrone in pharmaceutical formulations with a flow cell containing gold electrodes from recordable compact discs. Muñoz, R.A., Matos, R.C., Angnes, L. Journal of pharmaceutical sciences. (2001) [Pubmed]
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