Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

van Ginneken, C. et al.

van Ginneken, Weyns, van Meir,

Stereologic evaluation of the pig gastric wall and of somatostatinergic and serotoninergic immunoreactive mucosal cells during perinatal development.

A quantitative morphological study using stereologic methods was performed on vertical paraffin sections of the stomach of fetal and neonatal pigs. The sections were processed for 5-HT- and SOM-immunohistochemistry. In the neonatal pigs, the volume density of the submucosal layer in the pyloric gland region was approximately 15% less compared to the cardiac gland region. This suggests that altered functional demands after birth are temporarily related to and perhaps could promote the morphological diversification between the gastric regions. The distribution of 5-HT-IR and SOM-IR mucosal cells corresponds with previous observations in the adult mammalian stomach. However, based upon our results an age-dependent maturity or even different role is suspected for 5-HT and SOM. This is substantiated by the 4-fold rise of the volume occupied by 5-HT-IR mucosal cells in the pyloric gland region during development. Secondly, the regional differences of the volume density of SOM-IR mucosal cells vary according to developmental stage. The developmental variations of 5-HT- and SOM-IR mucosal cells contrast with findings in the rodent stomach. However, they are comparable to observations in man.[1]

References

Stereologic evaluation of the pig gastric wall and of somatostatinergic and serotoninergic immunoreactive mucosal cells during perinatal development. van Ginneken, C., Weyns, A., van Meir, E. European journal of morphology. (2001) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.