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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The antimicrobial activity of C-reactive protein.

Recent studies in transgenic mice confirmed that C-reactive protein is protective against microbial pathogens. This is consistent with its ability in vitro to bind microbes, activate the complement classical pathway, and engage FcgammaRI and FcgammaRII. However, in transgenic mice protection also requires the alternative pathway of complement, and FcgammaRI is dispensable.[1]

References

  1. The antimicrobial activity of C-reactive protein. Szalai, A.J. Microbes Infect. (2002) [Pubmed]
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