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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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N-alkylaminoacids and their derivatives interact with melanocortin receptors.

Thirty four N-alkylaminoacids (Arg, Trp, Nal, Pro, Hyp, L and D) and derivatives were prepared by a process that included reductive alkylation of the amino function. Both solid phase and solution synthesis was used. Title substances displayed binding activity on melanocortin receptors MC(1,3-5) reaching the low micromolar range.[1]

References

  1. N-alkylaminoacids and their derivatives interact with melanocortin receptors. Mutulis, F., Mutule, I., Wikberg, J.E. Bioorg. Med. Chem. Lett. (2002) [Pubmed]
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