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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Time-temperature study of the kinetics of migration of BADGE (bisphenol-A-diglycidyl-ether) into a fatty medium.

The migration kinetics of bisphenol-A-diglycidyl-ether (BADGE) from processed and non-processed model cans into vegetable oil was investigated as a function of the process treatment and the temperature of storage. Cans were either not heat-treated at all or were processed at 115 degrees C for 30 min or for 1 h after filling with oil. Each series of experiments comprised 30 samples and was further divided into three groups to be stored at different temperatures (20, 40 and 60 degrees C). Aliquots from the samples were taken at regular intervals for > 1 year. Samples were analysed for BADGE by high-performance liquid chromatography with fluorescence detection. The results showed that temperature processing had the largest effect on migration of BADGE. Storage temperature also significantly influenced migration from non-processed cans, in particular at higher storage temperatures such as 60 degrees C. Some samples were Subjected to 60 degrees C storage after an initial period at 20 degrees C and an effect on migration was also noted, although to a much lesser extent than from processing. The results of migration at higher temperatures were also correlated to the potential degradation of BADGE from oxidation products.[1]


  1. Time-temperature study of the kinetics of migration of BADGE (bisphenol-A-diglycidyl-ether) into a fatty medium. Simoneau, C., Theobald, A., Roncari, P., Hannaert, P., Anklam, E. Food additives and contaminants. (2002) [Pubmed]
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