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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors.

The structure-based design of potent and selective urokinase-type plasminogen activator (uPA) inhibitors with 4-aminoarylamidine or 4-aminoarylguanidine S1 binding groups, is described.[1]

References

  1. 4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors. Spencer, J.R., McGee, D., Allen, D., Katz, B.A., Luong, C., Sendzik, M., Squires, N., Mackman, R.L. Bioorg. Med. Chem. Lett. (2002) [Pubmed]
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