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Nostro, A. et al.

Nostro, Cannatelli, Musolino, Procopio, Alonzo,

Helichrysum italicum extract interferes with the production of enterotoxins by Staphylococcus aureus.

AIMS: The purpose of this work was to evaluate the effect of Helichrysum italicum extract on enterotoxin (A-D) production by Staphylococcus aureus strains. METHODS AND RESULTS: The production of enterotoxins A-D in the presence or absence of H.italicum diethyl ether extract was estimated in microtiter plates using a reversed passive latex agglutination (SET-RPLA) kit (Oxoid, Basingstoke, UK). The results indicate that, in culture medium, inhibition of staphylococcal growth and enterotoxins appeared with 250-125 microg ml(-1) of the extract. Lower concentrations of the extract (62.5-31.25 microg ml(-1)) did not affect the final viable count of Staph. aureus but reduced the production of enterotoxins B and C. CONCLUSIONS: H. italicum interferes with growth and production of enterotoxins by Staph. aureus. SIGNIFICANCE AND IMPACT OF THE STUDY: There is considerable interest in the use of natural compounds as alternative methods to control undesirable pathogenic micro-organisms.[1]

References

Helichrysum italicum extract interferes with the production of enterotoxins by Staphylococcus aureus. Nostro, A., Cannatelli, M.A., Musolino, A.D., Procopio, F., Alonzo, V. Lett. Appl. Microbiol. (2002) [Pubmed]

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