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Ankyloblepharon filiforme adnatum ( AFA) associated with trisomy 18.

Ankyloblepharon filiforme adnatum ( AFA) is a rare congenital anomaly which is characterized by single or multiple strands joining the upper and lower lids. Its etiology is unknown. A girl with a gestational age of 38 weeks is presented. It was interesting to find an association of AFA with hypoplasia of hair, eyelashes, eyebrows and nails and a karyotype of trisomy 18 in this case.[1]


  1. Ankyloblepharon filiforme adnatum (AFA) associated with trisomy 18. Tüysüz, B., Ilikkan, B., Vural, M., Perk, Y. Turk. J. Pediatr. (2002) [Pubmed]
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