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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Metabolic and immunological effects of antiretroviral agents in healthy individuals receiving post-exposure prophylaxis.

We have assessed metabolic and immunological effects of a nelfinavir-containing regimen in healthy HIV-1-uninfected individuals receiving post-exposure prophylaxis. Our data suggest that this regimen is well tolerated and did not modify the lipid or hepatic profiles. This antiretroviral regimen seems to have no effect on lymphocyte T cell subsets, however, it could have an immune-modulator role, inducing an increase in the proliferative responses to mitogens.[1]

References

  1. Metabolic and immunological effects of antiretroviral agents in healthy individuals receiving post-exposure prophylaxis. Garcia, F., Plana, M., Mestre, G., Cruceta, A., Martinez, E., Miró, J.M., Mallolas, J., Tuset, M., Pumorola, T., Gallart, T., Gatell, J.M. Antivir. Ther. (Lond.) (2002) [Pubmed]
 
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