Dynactin polices two-way organelle traffic.
How is the bidirectional motion of organelles controlled? In this issue, Deacon et al. (2003) reveal the unexpected finding that dynactin (previously known to control dynein-based motility) binds to kinesin II and regulates anterograde movement of Xenopus melanosomes. This result suggests that dynactin may be a key player in coordinating vesicle traffic in this system.[1]References
- Dynactin polices two-way organelle traffic. Dell, K.R. J. Cell Biol. (2003) [Pubmed]
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