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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Characterization of the human HOX 7 cDNA and identification of polymorphic markers.

cDNA clones for a human HOX 7 gene obtained with homologous clones of Drosophila were used in human gene mapping studies. The human cDNA clone was isolated from a library constructed from human embryonic craniofacial material. The sequence of the cDNA demonstrates significant homology with mouse HOX 7. A search for RFLPs identified MboII and BstEII variants. A CA dinucleotide repeat with 5 alleles was also identified and allowed placement of HOX 7 into a defined linkage map. Evidence for linkage disequilibrium was found with markers tested. These results place the human HOX 7 gene in a defined position on 4p.[1]


  1. Characterization of the human HOX 7 cDNA and identification of polymorphic markers. Padanilam, B.J., Stadler, H.S., Mills, K.A., McLeod, L.B., Solursh, M., Lee, B., Ramirez, F., Buetow, K.H., Murray, J.C. Hum. Mol. Genet. (1992) [Pubmed]
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