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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Gene switching by metabolic enzymes--how did you get on the invitation list?

Histone gene expression in mammalian cells is codependent upon the Oct-1 transcription factor and its cognate, OCA-S coactivator complex. Surprisingly, GADPH plays an essential role in the OCA-S complex and confers redox dependence upon the in vitro transcription of histone genes.[1]

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