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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

No association of germline alteration of MSR1 with prostate cancer risk.

The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.[1]


  1. No association of germline alteration of MSR1 with prostate cancer risk. Wang, L., McDonnell, S.K., Cunningham, J.M., Hebbring, S., Jacobsen, S.J., Cerhan, J.R., Slager, S.L., Blute, M.L., Schaid, D.J., Thibodeau, S.N. Nat. Genet. (2003) [Pubmed]
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