Gene Review:
MSR1 - macrophage scavenger receptor 1
Homo sapiens
Synonyms:
CD204, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, SR-A, ...
Seppälä,
Ikonen,
Autio,
Rökman,
Mononen,
Matikainen,
Tammela,
Schleutker,
Dinis,
Santosa,
Almeida,
Rennert,
Zeigler-Johnson,
Addya,
Finley,
Walker,
Spangler,
Leonard,
Wein,
Malkowicz,
Rebbeck,
Lange,
Gillanders,
Davis,
Brown,
Campbell,
Jones,
Gildea,
Riedesel,
Albertus,
Freas-Lutz,
Markey,
Giri,
Dimmer,
Montie,
Trent,
Cooney,
Maier,
Vesovic,
Bachmann,
Herkommer,
Braun,
Surowy,
Assum,
Paiss,
Vogel,
De Winther,
Gijbels,
Van Dijk,
Havekes,
Hofker,
Hsu,
Hajjar,
Khan,
Falcone,
Schaid,
- Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer. Nupponen, N.N., Wallén, M.J., Ponciano, D., Robbins, C.M., Tammela, T.L., Vessella, R.L., Carpten, J.D., Visakorpi, T. Genes Chromosomes Cancer (2004)
- Mutational analysis of the macrophage scavenger receptor 1 (MSR1) gene in primary lung cancer. Yoshimura, A., Gemma, A., Kataoka, K., Hosoya, Y., Noro, R., Seike, M., Kokubo, Y., Watanabe, M., Kudoh, S. Journal of Nippon Medical School = Nihon Ika Daigaku zasshi. (2004)
- A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake. Gough, P.J., Greaves, D.R., Gordon, S. J. Lipid Res. (1998)
- Production, characterization, and interspecies reactivities of monoclonal antibodies against human class A macrophage scavenger receptors. Tomokiyo, R., Jinnouchi, K., Honda, M., Wada, Y., Hanada, N., Hiraoka, T., Suzuki, H., Kodama, T., Takahashi, K., Takeya, M. Atherosclerosis (2002)
- Reduced infiltration of class A scavenger receptor positive antigen-presenting cells is associated with prostate cancer progression. Yang, G., Addai, J., Tian, W.H., Frolov, A., Wheeler, T.M., Thompson, T.C. Cancer Res. (2004)
- No association of germline alteration of MSR1 with prostate cancer risk. Wang, L., McDonnell, S.K., Cunningham, J.M., Hebbring, S., Jacobsen, S.J., Cerhan, J.R., Slager, S.L., Blute, M.L., Schaid, D.J., Thibodeau, S.N. Nat. Genet. (2003)
- Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Xu, J., Zheng, S.L., Komiya, A., Mychaleckyj, J.C., Isaacs, S.D., Hu, J.J., Sterling, D., Lange, E.M., Hawkins, G.A., Turner, A., Ewing, C.M., Faith, D.A., Johnson, J.R., Suzuki, H., Bujnovszky, P., Wiley, K.E., DeMarzo, A.M., Bova, G.S., Chang, B., Hall, M.C., McCullough, D.L., Partin, A.W., Kassabian, V.S., Carpten, J.D., Bailey-Wilson, J.E., Trent, J.M., Ohar, J., Bleecker, E.R., Walsh, P.C., Isaacs, W.B., Meyers, D.A. Nat. Genet. (2002)
- PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Chinetti, G., Lestavel, S., Bocher, V., Remaley, A.T., Neve, B., Torra, I.P., Teissier, E., Minnich, A., Jaye, M., Duverger, N., Brewer, H.B., Fruchart, J.C., Clavey, V., Staels, B. Nat. Med. (2001)
- A link between diabetes and atherosclerosis: Glucose regulates expression of CD36 at the level of translation. Griffin, E., Re, A., Hamel, N., Fu, C., Bush, H., McCaffrey, T., Asch, A.S. Nat. Med. (2001)
- Macrophage-colony-stimulating factor selectively enhances macrophage scavenger receptor expression and function. de Villiers, W.J., Fraser, I.P., Hughes, D.A., Doyle, A.G., Gordon, S. J. Exp. Med. (1994)
- Transforming growth factor-beta 1 inhibits scavenger receptor activity in THP-1 human macrophages. Bottalico, L.A., Wager, R.E., Agellon, L.B., Assoian, R.K., Tabas, I. J. Biol. Chem. (1991)
- The apoprotein is the preferential target for peroxynitrite-induced LDL damage protection by dietary phenolic acids. Dinis, T.C., Santosa, C.L., Almeida, L.M. Free Radic. Res. (2002)
- Mutation screening and association study of RNASEL as a prostate cancer susceptibility gene. Maier, C., Haeusler, J., Herkommer, K., Vesovic, Z., Hoegel, J., Vogel, W., Paiss, T. Br. J. Cancer (2005)
- Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men. Rennert, H., Zeigler-Johnson, C.M., Addya, K., Finley, M.J., Walker, A.H., Spangler, E., Leonard, D.G., Wein, A., Malkowicz, S.B., Rebbeck, T.R. Cancer Epidemiol. Biomarkers Prev. (2005)
- HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors. Nakamura, T., Hinagata, J., Tanaka, T., Imanishi, T., Wada, Y., Kodama, T., Doi, T. Biochem. Biophys. Res. Commun. (2002)
- Germline mutations of the MSR1 gene in prostate cancer families from Germany. Maier, C., Vesovic, Z., Bachmann, N., Herkommer, K., Braun, A.K., Surowy, H.M., Assum, G., Paiss, T., Vogel, W. Hum. Mutat. (2006)
- Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages. de Winther, M.P., van Dijk, K.W., van Vlijmen, B.J., Gijbels, M.J., Heus, J.J., Wijers, E.R., van den Bos, A.C., Breuer, M., Frants, R.R., Havekes, L.M., Hofker, M.H. Atherosclerosis (1999)
- Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on cholesterol levels and atherosclerosis in ApoE-deficient mice. Van Eck, M., De Winther, M.P., Herijgers, N., Havekes, L.M., Hofker, M.H., Groot, P.H., Van Berkel, T.J. Arterioscler. Thromb. Vasc. Biol. (2000)
- Transgenic mouse models to study the role of the macrophage scavenger receptor class A in atherosclerosis. De Winther, M.P., Gijbels, M.J., Van Dijk, K.W., Havekes, L.M., Hofker, M.H. International journal of tissue reactions. (2000)
- Expression of class A scavenger receptor is enhanced by high glucose in vitro and under diabetic conditions in vivo: one mechanism for an increased rate of atherosclerosis in diabetes. Fukuhara-Takaki, K., Sakai, M., Sakamoto, Y., Takeya, M., Horiuchi, S. J. Biol. Chem. (2005)
- Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway. Hsu, H.Y., Hajjar, D.P., Khan, K.M., Falcone, D.J. J. Biol. Chem. (1998)
- Alpha-tocopherol down-regulates scavenger receptor activity in macrophages. Teupser, D., Thiery, J., Seidel, D. Atherosclerosis (1999)
- A Unique Loop Extension in the Serine Protease Domain of Haptoglobin Is Essential for CD163 Recognition of the Haptoglobin-Hemoglobin Complex. Nielsen, M.J., Petersen, S.V., Jacobsen, C., Thirup, S., Enghild, J.J., Graversen, J.H., Moestrup, S.K. J. Biol. Chem. (2007)
- Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene. Wu, H., Moulton, K., Horvai, A., Parik, S., Glass, C.K. Mol. Cell. Biol. (1994)
- Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulated. Hsu, H.Y., Nicholson, A.C., Hajjar, D.P. J. Biol. Chem. (1996)
- The complex genetic epidemiology of prostate cancer. Schaid, D.J. Hum. Mol. Genet. (2004)
- Genome-wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1. Lange, E.M., Gillanders, E.M., Davis, C.C., Brown, W.M., Campbell, J.K., Jones, M., Gildea, D., Riedesel, E., Albertus, J., Freas-Lutz, D., Markey, C., Giri, V., Dimmer, J.B., Montie, J.E., Trent, J.M., Cooney, K.A. Prostate (2003)
- Mutation screening and association study of the candidate prostate cancer susceptibility genes MSR1, PTEN, and KLF6. Bar-Shira, A., Matarasso, N., Rosner, S., Bercovich, D., Matzkin, H., Orr-Urtreger, A. Prostate (2006)
- Germ-line alterations in MSR1 gene and prostate cancer risk. Seppälä, E.H., Ikonen, T., Autio, V., Rökman, A., Mononen, N., Matikainen, M.P., Tammela, T.L., Schleutker, J. Clin. Cancer Res. (2003)
- Germ-line mutations of the macrophage scavenger receptor 1 gene: association with prostate cancer risk in African-American men. Miller, D.C., Zheng, S.L., Dunn, R.L., Sarma, A.V., Montie, J.E., Lange, E.M., Meyers, D.A., Xu, J., Cooney, K.A. Cancer Res. (2003)
- Structure, organization, and chromosomal mapping of the human macrophage scavenger receptor gene. Emi, M., Asaoka, H., Matsumoto, A., Itakura, H., Kurihara, Y., Wada, Y., Kanamori, H., Yazaki, Y., Takahashi, E., Lepert, M. J. Biol. Chem. (1993)
- Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors. Ashkenas, J., Penman, M., Vasile, E., Acton, S., Freeman, M., Krieger, M. J. Lipid Res. (1993)