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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Separation of reduced and oxidized glutathione in a pharmaceutical preparation by ion-interaction reversed-phase HPLC.

A new method is presented for the simultaneous determination of reduced and oxidized glutathione by ion-interaction reversed-phase HPLC with octylamine orthophosphate as the interaction reagent, 5-microns Spherisorb ODS-2 as the stationary phase and UV detection at 230 nm. Lower limits of detection of 2.50 micrograms ml-1 have been achieved for both the oxidized and the reduced forms. The method has been applied in the analysis of a commercial pharmaceutical preparation.[1]

References

  1. Separation of reduced and oxidized glutathione in a pharmaceutical preparation by ion-interaction reversed-phase HPLC. Gennaro, M.C., Abrigo, C. Journal of pharmaceutical and biomedical analysis. (1992) [Pubmed]
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