The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Cytochemical characterization of the cuticle of Caenorhabditis elegans (Nematoda: Rhabditoidea).

At the ultrastructural level, the Caenorhabditis elegans (Maupas, 1900; Doughert, 1953) cuticle shows the presence of six layers: epicuticle, external cortical, internal cortical, intermediate, fibrous and basal. Two techniques were used for carbohydrate localization: the periodic acid-thiosemicarbazide-silver proteinate (Thiéry) and gold-labelled lectins. No labelling was found on the nematode's cuticle. With the ethanolic phosphotungstic acid technique (E-PTA), that detects basic proteins, reaction product was observed in the outer cortical layer, in the cuticle struts and in the dense bodies of the muscle cell. Surface anionic sites of C. elegans were visualized by using cationized ferritin particles, at pH 7.2, and by using colloidal iron hydroxide particles at pH 1. 8. Treatments with trypsin and neuraminidase (Vibrio cholerae) did not interfere with the binding of the cationic particles to the nematode's surface. In contrast, treatment with chondroitinase ABC, a specific enzyme for glycosaminoglycans, significantly reduced the binding.[1]


  1. Cytochemical characterization of the cuticle of Caenorhabditis elegans (Nematoda: Rhabditoidea). Peixoto, C.A., De Souza, W. J. Submicrosc. Cytol. Pathol. (1992) [Pubmed]
WikiGenes - Universities