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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Efficacy of voriconazole in treatment of systemic scedosporiosis in neutropenic mice.

We have evaluated the efficacy of voriconazole (VRC) in a murine model of systemic infection by Scedosporium apiospermum. The survival of mice treated with VRC at 5, 20, or 40 mg/kg/day was greater than that of the control group (P< or =0.0009). VRC reduced the tissue burden in the spleen and brain (P<0.001 in both organs) in comparison with that of the control group.[1]

References

  1. Efficacy of voriconazole in treatment of systemic scedosporiosis in neutropenic mice. Capilla, J., Serena, C., Pastor, F.J., Ortoneda, M., Guarro, J. Antimicrob. Agents Chemother. (2003) [Pubmed]
 
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