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MeSH Review


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Disease relevance of Scedosporium


High impact information on Scedosporium


Chemical compound and disease context of Scedosporium


Biological context of Scedosporium


Anatomical context of Scedosporium


Associations of Scedosporium with chemical compounds


Gene context of Scedosporium

  • Thus, IFN-gamma and GM-CSF, particularly in combination, demonstrate a species- and time-dependent augmentation of PMN responses to Scedosporium spp [19].
  • An extracellular proteinase produced by the filamentous fungus Scedosporium apiospermum has been purified and characterized [18].
  • Molecular typing of clinical and environmental isolates of Scedosporium prolificans by inter-simple-sequence-repeat polymerase chain reaction [20].

Analytical, diagnostic and therapeutic context of Scedosporium


  1. Keratitis caused by Scedosporium apiospermum successfully treated with a cornea transplant and voriconazole. Nulens, E., Eggink, C., Rijs, A.J., Wesseling, P., Verweij, P.E. J. Clin. Microbiol. (2003) [Pubmed]
  2. Scedosporium apiospermum soft tissue infection successfully treated with voriconazole: potential pitfalls in the transition from intravenous to oral therapy. Schaenman, J.M., Digiulio, D.B., Mirels, L.F., McClenny, N.M., Berry, G.J., Fothergill, A.W., Rinaldi, M.G., Montoya, J.G. J. Clin. Microbiol. (2005) [Pubmed]
  3. Successful treatment of Scedosporium apiospermum suppurative arthritis with itraconazole. Piper, J.P., Golden, J., Brown, D., Broestler, J. Pediatr. Infect. Dis. J. (1990) [Pubmed]
  4. Treatment of Scedosporium apiospermum brain abscesses with posaconazole. Mellinghoff, I.K., Winston, D.J., Mukwaya, G., Schiller, G.J. Clin. Infect. Dis. (2002) [Pubmed]
  5. Pulmonary scedosporium infection following lung transplantation. Tamm, M., Malouf, M., Glanville, A. Transplant infectious disease : an official journal of the Transplantation Society. (2001) [Pubmed]
  6. Airborne outbreak of nosocomial Scedosporium prolificans infection. Guerrero, A., Torres, P., Duran, M.T., Ruiz-Díez, B., Rosales, M., Rodriguez-Tudela, J.L. Lancet (2001) [Pubmed]
  7. In vitro pharmacodynamics of amphotericin B, itraconazole, and voriconazole against Aspergillus, Fusarium, and Scedosporium spp. Lewis, R.E., Wiederhold, N.P., Klepser, M.E. Antimicrob. Agents Chemother. (2005) [Pubmed]
  8. In vitro synergistic interaction between amphotericin B and micafungin against Scedosporium spp. Yustes, C., Guarro, J. Antimicrob. Agents Chemother. (2005) [Pubmed]
  9. In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi. Cuenca-Estrella, M., Gomez-Lopez, A., Mellado, E., Garcia-Effron, G., Monzon, A., Rodriguez-Tudela, J.L. Antimicrob. Agents Chemother. (2005) [Pubmed]
  10. Antifungal activities of posaconazole and granulocyte-macrophage colony-stimulating factor ex vivo and in mice with disseminated infection due to Scedosporium prolificans. Simitsopoulou, M., Gil-Lamaignere, C., Avramidis, N., Maloukou, A., Lekkas, S., Havlova, E., Kourounaki, L., Loebenberg, D., Roilides, E. Antimicrob. Agents Chemother. (2004) [Pubmed]
  11. Cutaneous infection due to Scedosporium apiospermum in an immunosuppressed patient. Chaveiro, M.A., Vieira, R., Cardoso, J., Afonso, A. Journal of the European Academy of Dermatology and Venereology : JEADV. (2003) [Pubmed]
  12. Changes in the cellular content of the pool constituents of Monosporium olivaceum -- a steroid hydroxylating mould. Jaworski, A., Długoński, J., Wilmańska, D., Sedlaczek, L. Acta Microbiol. Pol. (1976) [Pubmed]
  13. In vitro studies of activity of voriconazole (UK-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens. Radford, S.A., Johnson, E.M., Warnock, D.W. Antimicrob. Agents Chemother. (1997) [Pubmed]
  14. Effects of interleukin-15 on antifungal responses of human polymorphonuclear leukocytes against Fusarium spp. and Scedosporium spp. Winn, R.M., Gil-Lamaignere, C., Roilides, E., Simitsopoulou, M., Lyman, C.A., Maloukou, A., Walsh, T.J. Cytokine (2005) [Pubmed]
  15. Efficacy of voriconazole in treatment of systemic scedosporiosis in neutropenic mice. Capilla, J., Serena, C., Pastor, F.J., Ortoneda, M., Guarro, J. Antimicrob. Agents Chemother. (2003) [Pubmed]
  16. In vitro activities of four novel triazoles against Scedosporium spp. Carrillo, A.J., Guarro, J. Antimicrob. Agents Chemother. (2001) [Pubmed]
  17. In vitro interaction of terbinafine with itraconazole against clinical isolates of Scedosporium prolificans. Meletiadis, J., Mouton, J.W., Rodriguez-Tudela, J.L., Meis, J.F., Verweij, P.E. Antimicrob. Agents Chemother. (2000) [Pubmed]
  18. A 33 kDa serine proteinase from Scedosporium apiospermum. Larcher, G., Cimon, B., Symoens, F., Tronchin, G., Chabasse, D., Bouchara, J.P. Biochem. J. (1996) [Pubmed]
  19. Inteferon gamma and granulocyte-macrophage colony-stimulating factor augment the antifungal activity of human polymorphonuclear leukocytes against Scedosporium spp.: comparison with Aspergillus spp. Gil-Lamaignere, C., Winn, R.M., Simitsopoulou, M., Maloukou, A., Walsh, T.J., Roilides, E. Med. Mycol. (2005) [Pubmed]
  20. Molecular typing of clinical and environmental isolates of Scedosporium prolificans by inter-simple-sequence-repeat polymerase chain reaction. Solé, M., Cano, J., Rodríguez-Tudela, J.L., Pontón, J., Sutton, D.A., Perrie, R., Gené, J., Rodríguez, V., Guarro, J. Med. Mycol. (2003) [Pubmed]
  21. Successful bone marrow transplantation in patients with previous invasive fungal infections: report of four cases. Martino, R., Nomdedéu, J., Altés, A., Sureda, A., Brunet, S., Martínez, C., Domingo-Albós, A. Bone Marrow Transplant. (1994) [Pubmed]
  22. Recurrence of Scedosporium apiospermum infection following renal re-transplantation. Ahmed, J., Ditmars, D.M., Sheppard, T., del Busto, R., Venkat, K.K., Parasuraman, R. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. (2004) [Pubmed]
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