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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Spirituality, well-being, and quality of life in people with rheumatoid arthritis.

OBJECTIVE: To evaluate spirituality, well-being, and quality of life (QOL) among people with rheumatoid arthritis ( RA). METHODS: Questionnaires assessing positive and negative affect, depression, QOL and spirituality were completed. Disease activity was assessed by rheumatologic examination. RESULTS: Women (n = 62) had a mean (+/- SD) age of 53.0 (+/- 13.0) years with 12 (+/- 13) swollen and tender joints (STJ). Men (n = 15) were 61.9 (+/- 13.0) years with 7 (+/- 11) STJ. Disease activity was associated (P < 0.05) positively with depression (r = 0.23), pain (r = 0.26), poorer self-ratings of health (r = 0.29) and physical role limitations (r = 0.26). Spirituality was associated directly with positive affect (r = 0.26) and higher health perceptions (r = 0.29). In multiple regression, spirituality was an independent predictor of happiness and positive health perceptions, even after controlling disease activity and physical functioning, for age and mood. CONCLUSION: Spirituality may facilitate emotional adjustment and resilience in people with RA by experiencing more positive feelings and attending to positive elements of their lives.[1]


  1. Spirituality, well-being, and quality of life in people with rheumatoid arthritis. Bartlett, S.J., Piedmont, R., Bilderback, A., Matsumoto, A.K., Bathon, J.M. Arthritis Rheum. (2003) [Pubmed]
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