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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Prognostic value of the MIB-1 labeling index for central neurocytomas.

Although central neurocytomas are generally described as benign CNS lesions, malignant behavior including craniospinal dissemination and tumor-related death may occur. This meta-analysis was performed to investigate the prognostic value of the MIB-1 labeling index. Data were obtained not from the literature alone but also from contact with the authors. The data suggested an MIB-1 index score of >3% to be associated with a worse prognosis for local control (p < 0.0001) and survival (p = 0.0004).[1]

References

  1. Prognostic value of the MIB-1 labeling index for central neurocytomas. Rades, D., Schild, S.E., Fehlauer, F. Neurology (2004) [Pubmed]
 
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