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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Driven to autoimmunity: the nod mouse.

In the lymphoid system, T cells respond to space or under-crowding by dividing to maintain their numbers. In this issue of Cell, evidence is provided that this homeostatic proliferation, coupled with excess production of a cytokine, IL-21, is a key factor in susceptibility to autoimmune diabetes.[1]

References

  1. Driven to autoimmunity: the nod mouse. Gallegos, A.M., Bevan, M.J. Cell (2004) [Pubmed]
 
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