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MeSH Review

Diabetes Mellitus, Type 1

 
 
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Disease relevance of Diabetes Mellitus, Type 1

 

Psychiatry related information on Diabetes Mellitus, Type 1

 

High impact information on Diabetes Mellitus, Type 1

 

Chemical compound and disease context of Diabetes Mellitus, Type 1

 

Biological context of Diabetes Mellitus, Type 1

 

Anatomical context of Diabetes Mellitus, Type 1

 

Gene context of Diabetes Mellitus, Type 1

  • The role of Fas in autoimmune diabetes [30].
  • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha [31].
  • These studies demonstrate that costimulatory signals play an important role in the autoimmune process, and that different members of the B7 family have distinct regulatory functions during the development of autoimmune diabetes [32].
  • Early treatment with LTbetaR-Ig prevented insulitis and IDDM, suggesting that LT plays a critical role in the insulitis development [33].
  • It is concluded that expression of a hybrid insulin/IL-1ra gene confers resistance to IL-1 and that this technique may be used to elucidate the role of IL-1 in autoimmune disorders such as insulin-dependent diabetes mellitus [34].
 

Analytical, diagnostic and therapeutic context of Diabetes Mellitus, Type 1

References

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