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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children.

We studied a nucleoside reverse transcriptase inhibitor (NRTI)-sparing regimen for the treatment of children infected with NRTI-resistant HIV-1. The combination of lopinavir/ritonavir and efavirenz suppressed HIV-1 levels for a prolonged period and resulted in a significant increase in CD4+ T cell numbers despite an extensive prior treatment with NRTI (>4 years). Observed side effects were transient with the exception of dyslipidaemia.[1]

References

  1. Safety and efficacy of a NRTI-sparing HAART regimen of efavirenz and lopinavir/ritonavir in HIV-1-infected children. Fraaij, P.L., Neubert, J., Bergshoeff, A.S., van Rossum, A.M., Hartwig, N.G., Schroten, H., Korn, K., Burger, D.M., de Groot, R., Niehues, T. Antivir. Ther. (Lond.) (2004) [Pubmed]
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