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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Salmonella gene rma (ramA) and multiple-drug-resistant Salmonella enterica serovar typhimurium.

MarA and its homologue, RamA, have been implicated in multidrug resistance ( MDR). RamA overexpression in Salmonella enterica serovar Typhimurium and Escherichia coli conferred MDR independently of marA. Inactivation of ramA did not affect the antibiotic susceptibilities of wild-type S. enterica serovar Typhimurium or 15 unrelated clinical MDR isolates. Thus, ramA overexpression is not a common MDR mechanism in Salmonella.[1]

References

  1. Salmonella gene rma (ramA) and multiple-drug-resistant Salmonella enterica serovar typhimurium. van der Straaten, T., Janssen, R., Mevius, D.J., van Dissel, J.T. Antimicrob. Agents Chemother. (2004) [Pubmed]
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