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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models.

Highlights from a Fundación Juan March Interdisciplinary Meeting. CD8+ T cells (TCD8+) play a critical role in immunity to viruses. A central feature of antiviral TCD8+ responses is immunodominance: out of thousands of potential target peptides, only a handful generate measurable responses. A recent Fundación Juan March Meeting brought together scientists working on the various steps in antigen presentation and T cell biology that contribute to immunodominance, whose understanding is key to rationally developing vaccines meant to elicit effective antiviral TCD8+ responses.[1]

References

  1. Immunodominance in TCD8+ responses to viruses: cell biology, cellular immunology, and mathematical models. Yewdell, J.W., Del Val, M. Immunity (2004) [Pubmed]
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